Bureau of Industry and Security of the US Department of Commerce. Its mission is to advance U.S. national security, foreign policy, and economic objectives by ensuring an effective export control and treaty compliance system and promoting continued U.S. strategic technology leadership. BIS implements U.S. government sanctions against Cuba, Iran, North Korea, Sudan, and Syria pursuant to the EAR, either unilaterally or to implement UN Security Council Resolutions. The license requirements, license exceptions, and licensing policy vary depending upon the particular sanctioned destination. The BIS-Department of Commerce website is a useful resource for information on which destinations are subject to foreign policy related controls.
See: http://www.bis.doc.gov/index.php/policy-guidance/country-guidance/sanctioned-destinations

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